Dominique Durand

Professor, Biomedical Engineering Director, Neural Engineering Center
Analyses neural systems and designs devices to interface with the nervous system to provide therapies for neurological disorders
Office: WiCK 112 Wickenden Phone Number: (216) 368-3974 Fax Number: (216) 368-4872 Email: dxd6@case.edu

Research Interests

Neural engineering, computational neuroscience, neural interfacing, neurophysiology and control of epilepsy, non-linear dynamics of neural systems, neural prostheses and neuromodutation

Teaching Interests

Biomedical Intrumentation, Bioelectricity, Undergraduate Research Experience

Patents Received

Publications

Wu, Y., Chien, M., Huang, C., Chiang, C., Lin, C., Huang, C., Durand, D. M., & Hsu, K. M. (2020). Transcranial direct current stimulation alleviates seizure severity in kainic acid-induced status epilepticus rats. Experimental Neurology, 328
Couturier, N., & Durand, D. M. (2020). Comparison of fiber tract low frequency stimulation to focal and ANT stimulation in an acute rat model of focal cortical seizures. Brain Stimulation, 13 (2), 499-506.
Shivacharan, R., Chiang, C., Zhang, M., Gonzalez-Reyes, L., & Durand, D. M. (2019). Self-propagating, non-synaptic epileptiform activity recruits neurons by endogenous electric fields. Experimental Neurology, 317 , 119-128.
Shivacharan, R., Chiang, C., & Durand, D. M. (2019). Abstract #110: Ephaptic coupling, a mechanism for spontaneous neural propagation in the brain. Brain Stimulation, 12 (2).
Zhu, F., Zhu, J., Zhang, G., Wang, Y., Su, J., McCallum, G., Zhang, X., Sui, X., & Durand, D. M. (2019). Flexural characterization of carbon nanotube (CNT) yarn neural electrodes. Materials Research Express, 6 (4).
Chiang, C., Shivacharan, R., Wei, X., Gonzalez-Reyes, L., & Durand, D. M. (2019). Slow periodic activity in the longitudinal hippocampal slice can self-propagate non-synaptically by a mechanism consistent with ephaptic coupling: Slow periodic activity by ephaptic coupling. Journal of Physiology, 597 (1), 249-269.
Eggers, T., Dweiri, Y., McCallum, G., & Durand, D. M. (2018). Recovering Motor Activation with Chronic Peripheral Nerve Computer Interface. Scientific Reports, 8 (1).
Chiang, C., Wei, X., Ananthakrishnan, A., Shivacharan, R., Gonzalez-Reyes, L., Zhang, M., & Durand, D. M. (2018). Slow moving neural source in the epileptic hippocampus can mimic progression of human seizures. Scientific Reports, 8 (1).
Eggers, T., Dweiri, Y., McCallum, G., & Durand, D. M. (2017). Model-based Bayesian signal extraction algorithm for peripheral nerves. Journal of Neural Engineering, 14 (5).
McCallum, G., Sui, X., Qiu, C., Marmerstein, J., Zheng, Y., Eggers, T., Hu, C., Dai, L., & Durand, D. M. (2017). Chronic interfacing with the autonomic nervous system using carbon nanotube (CNT) yarn electrodes. Scientific Reports, 7 (1).
Feng, Z., Wang, Z., Guo, Z., Zhou, W., Cai, Z., & Durand, D. M. (2017). High frequency stimulation of afferent fibers generates asynchronous firing in the downstream neurons in hippocampus through partial block of axonal conduction. Brain Research, 1661 , 67-78.
Dweiri, Y., Stone, M., Tyler, D. J., McCallum, G. J., & Durand, D. M. (2016). Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications. Journal of Visualized Experiments [1940087X].
Zhang, M., Shivacharan, R., Chiang, C., Gonzalez-Reyes, L., & Durand, D. M. (2016). Propagating Neural Source Revealed by Doppler Shift of Population Spiking Frequency. Journal of Neuroscience [02706474], 36 (12), 3495-3505.
Zhang, M., Kibler, A., Gonzales-Reyes, L., & Durand, D. M. (2015). Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array. .
Ladas, T., Chiang, C., Gonzalez-Reyes, L., Nowak, T., & Durand, D. M. (2015). Seizure reduction through interneuron-mediated entrainment using low frequency optical stimulation. , 269 , 120-132.
Dweiri, Y., Eggers, T., McCallum, G., & Durand, D. M. (2015). Ultra-low noise miniaturized neural amplifier with hardware averaging. , 12 (4), -.
Wang, Y., Toprani, S., Tang, Y., Vrabec, T., & Durand, D. M. (2014). Mechanism of highly synchronized bilateral hippocampal activity.. Experimental neurology, 251 , 101-11.
Caparso, A., Durand, D. M., & Mansour, J. M. (2009). A nerve cuff electrode for controlled reshaping of nerve geometry.. Journal of biomaterials applications, 24 (3), 247-73.
Tyler, D. J., & Durand, D. M. (2003). Chronic response of the rat sciatic nerve to the flat interface nerve electrode. Annals of biomedical engineering, 31 (6), 633--642.
Tyler, D. J., & Durand, D. M. (2002). Functionally selective peripheral nerve stimulation with a flat interface nerve electrode. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 10 (4), 294--303.
Qi, H., Tyler, D. J., & Durand, D. M. (1999). Neurofuzzy adaptive controlling of selective stimulation for FES: a case study. IEEE transactions on rehabilitation engineering, 7 (2), 183--192.
Bertrand, C., Durand, D. M., Saidel, G. M., Laboisse, C. M., & Hopfer, U. M. (1998). System for dynamic measurements of membrane capacitance in intact epithelial monolayers.. Biophysical journal, 75 (6), 2743-56.
Tyler, D. J., & Durand, D. M. (1997). A slowly penetrating interfascicular nerve electrode for selective activation of peripheral nerves. IEEE Transactions on Rehabilitation Engineering, 5 (1), 51--61.
Tyler, D. J., & Durand, D. M. (1994). Interfascicular electrical stimulation for selectively activating axons. IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE, 13 (4), 575--575.
Ali-Hassan, W., Saidel, G. M., & Durand, D. M. (1992). Estimation of electrotonic parameters of neurons using an inverse Fourier transform technique.. IEEE transactions on bio-medical engineering, 39 (5), 493-501.